DCU

Names

[ CAS No. ]:
116-52-9

[ Name ]:
DCU

[Synonym ]:
Experimental herbicide 2
Dichloraluree
1,3-BIS-(2,2,2-TRICHLORO-1-HYDROXY-ETHYL)-UREA
EINECS 204-144-7
MFCD00018836
1,3-BIS-(1-HYDROXY-2,2,2-TRICHLOROETHYL)-UREA
Crag DCU-73W
Dicloralurea
1,3-bis(2,2,2-trichloro-1-hydroxyethyl)urea
Crag herbicide 2
N,N’-bis(2,2,2-trichloro-1-hydroxyethyl)urea
F 1995
SKF 1995
Crag experimental herbicide 2
DCU
DICHLORAL UREA

Biological Activity

[Description]:

Dicloralurea is a veterinary food additive that inhibits methane production in herbicide ruminants, acts as a growth stimulant.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Others

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.867g/cm3

[ Boiling Point ]:
451.1ºC at 760 mmHg

[ Melting Point ]:
196ºC

[ Molecular Formula ]:
C₅H₆Cl₆N₂O₃

[ Molecular Weight ]:
354.83100

[ Flash Point ]:
226.6ºC

[ Exact Mass ]:
351.85100

[ PSA ]:
81.59000

[ LogP ]:
2.44460

[ Vapour Pressure ]:
4.92E-10mmHg at 25°C

[ Index of Refraction ]:
1.593

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YS2787000

CHEMICAL NAME :: Urea, 1,3-bis(2,2,2-trichloro-1-hydroxyethyl)-

CAS REGISTRY NUMBER :: 116-52-9

BEILSTEIN REFERENCE NO. :: 1813364

LAST UPDATED :: 199612

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C5-H6-Cl6-N2-O3

MOLECULAR WEIGHT :: 354.83

WISWESSER LINE NOTATION :: GXGGYQMVMYQXGGG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 6400 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Behavioral - ataxia

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 59100 ug/m3/17W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 59100 ug/m3/17W-I

TOXIC EFFECTS :: Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

REFERENCE :: CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974- Volume(issue)/page/year: 11(4),62,1977 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 5 mg/m3 JAN 1993

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
YS2787000

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

[Determination of the maximum allowable concentration of dichloralurea in the air of the workplace].

Gig. Tr. Prof. Zabol. (1) , 51-2, (1984)

DCU