Defensin HNP 4

Names

[ CAS No. ]:
116977-48-1

[ Name ]:
Defensin HNP 4

Biological Activity

[Description]:

Defensin HNP 4 (HNP 4) is a single 11 amino acid long fragment of HNP-41-11. Defensin HNP 4 has inhibitory effect against multidrug-resistant and non-resistant strains[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Defensin HNP 4 (1.56-100 μM; 2 h) 显示抗菌活性[1]。 Defensin HNP 4 (1.56-100 μM; 96 h) 对人结肠上皮腺癌细胞系 CaCo2 亚克隆 TC7 和结直肠癌细胞系 HT29 MTX 细胞亚克隆 E12 具有低细胞毒性[1]。 Defensin HNP 4 (1.56-100 μM; 1 h) 表现出溶血活性[1]。

[References]

[1]. Ehmann D, et al. Fragmentation of Human Neutrophil α-Defensin 4 to Combat Multidrug Resistant Bacteria. Front Microbiol. 2020 Jun 3;11:1147.

Chemical & Physical Properties

[ Molecular Formula ]:
C157H261N49O43S6

[ Molecular Weight ]:
3715.44

Related Compounds