Triptonediol

Names

[ Name ]:
Triptonediol

[Synonym ]:
11,19-Dihydroxy-14-methoxyabieta-8(14),9(11),12-trien-3-one
Triptonediol
2(1H)-Phenanthrenone, 3,4,4a,9,10,10a-hexahydro-5-hydroxy-1-(hydroxymethyl)-8-methoxy-1,4a-dimethyl-7-(1-methylethyl)-, (1S,4aS,10aR)-

Biological Activity

[Description]:

Triptonodiol can be isolated from Trypterygium wilfordii. Triptonodiol has anti-inflammatory and anti-cancer activity. Triptonodiol inhibits the biological activity of GSK[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Zhou BN, et al. Studies on New Components and Stereochemistry of Diterpenoids from Trypterygium wilfordii. Planta Med. 1988 Aug;54(4):330-2.

[2]. Feng Jin, et al. Network pharmacology‑based investigation of potential targets of Triptonodiol acting on Non-Small-Cell Lung Cancer. Research Square. 2023. DOI: 10.21203/rs.3.rs-2463976/v1

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
529.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₁H₃₀O₄

[ Molecular Weight ]:
346.46

[ Flash Point ]:
183.4±23.6 °C

[ Exact Mass ]:
346.214417

[ PSA ]:
66.76000

[ LogP ]:
3.69

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.546

Safety Information

[ Hazard Codes ]:
Xi