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DSP-1053

Names

[ CAS No. ]:
1176326-76-3

[ Name ]:
DSP-1053

Biological Activity

[Description]:

DSP-1053 is a potent Serotonin Transporter (SERT) (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonistic activity.

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter

[Target]

Ki: 1.02 nM (SERT), 1.02 nM (5-HT1A)[1]

[References]

[1]. Yoshinaga H, et al. Discovery of DSP-1053, a novel benzylpiperidine derivative with potent serotonin transporter inhibitory activity and partial 5-HT1A receptor agonistic activity. Bioorg Med Chem. 2018 May 1;26(8):1614-1627.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₂BrNO₄

[ Molecular Weight ]:
502.44

Related Compounds