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(+)-Blebbistatin

Names

[ CAS No. ]:
1177356-70-5

[ Name ]:
(+)-Blebbistatin

[Synonym ]:
(−)-Blebbistatin
(3aR)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
(3aR)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
Blebbistatin
(3aS)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aS)-
4H-Pyrrolo[2,3-b]quinolin-4-one, 1,2,3,3a-tetrahydro-3a-hydroxy-6-methyl-1-phenyl-, (3aR)-
(+)-Blebbistatin
(S)-Blebbistatin

Biological Activity

[Description]:

(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective inhibitor of myosin II ATPase[1].

[Related Catalog]:

Signaling Pathways >> Cytoskeleton >> Myosin
Research Areas >> Others

[References]

[1]. Cristina Lucas‐Lopez, et al. Absolute Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool, (–)‐Blebbistatin.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
507.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H16N2O2

[ Molecular Weight ]:
292.332

[ Flash Point ]:
260.6±32.9 °C

[ Exact Mass ]:
292.121185

[ PSA ]:
52.90000

[ LogP ]:
1.62

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.681

Related Compounds