N20C hydrochloride

Names

[ Name ]:
N20C hydrochloride

[Synonym ]:
Acetamide, 2-[(3,3-diphenylpropyl)amino]-, hydrochloride (1:1)
N2-(3,3-Diphenylpropyl)glycinamide hydrochloride (1:1)
MFCD06798327

Biological Activity

[Description]:

N20C hydrochloride is a selective and noncompetitive open NMDA receptor open channel blocker, with micromolar affinity, fast on-off blockade kinetics, and strong voltage dependence. Neuroprotective activity[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[References]

[1]. Rosa Planells-Cases, et al. A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity. J Pharmacol Exp Ther. 2002 Jul;302(1):163-73.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₂₁ClN₂O

[ Molecular Weight ]:
304.81

[ Exact Mass ]:
304.134247