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Hydrastine

Names

[ CAS No. ]:
118-08-1

[ Name ]:
Hydrastine

[Synonym ]:
Hydrastine (10 mg)
quinolin-5-yl)
HYDRASTINE
Hydrastinebase
(-)-Beta-Hydrastine
EINECS 204-233-0
MFCD00152561
(-)-B-HYDIASTINE
l-hydrastine
HYDRASTINE,(-)-B

Biological Activity

[Description]:

Hydrastine is a natural alkaloid which is present in Hydrastis canadensis and other plants of the ranunculaceae family.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Natural Products >> Alkaloid
Research Areas >> Others

[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.339g/cm3

[ Boiling Point ]:
548.8ºC at 760mmHg

[ Melting Point ]:
132ºC

[ Molecular Formula ]:
C21H21NO6

[ Molecular Weight ]:
383.39500

[ Flash Point ]:
285.7ºC

[ Exact Mass ]:
383.13700

[ PSA ]:
66.46000

[ LogP ]:
2.81110

[ Vapour Pressure ]:
4.28E-12mmHg at 25°C

[ Index of Refraction ]:
1.614

[ Storage condition ]:
−20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MU6030000
CHEMICAL NAME :
Hydrastine
CAS REGISTRY NUMBER :
118-08-1
BEILSTEIN REFERENCE NO. :
0098575
LAST UPDATED :
199709
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H21-N-O6
MOLECULAR WEIGHT :
383.43
WISWESSER LINE NOTATION :
T C566 DO FO LN EH&&TJ L M- DT56 BVO DHJ HO1 IO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
104 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P261-P280-P301 + P312 + P330

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
S36

[ RIDADR ]:
1544

[ WGK Germany ]:
3

[ RTECS ]:
MU6030000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Synthetic Route

Precursor & DownStream


Related Compounds