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Tafluprost ethyl amide

Names

[ CAS No. ]:
1185851-52-8

[ Name ]:
Tafluprost ethyl amide

[Synonym ]:
(5Z)-7-{(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl}-N-ethyl-5-heptenamide
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5-Heptenamide, 7-[(1R,2R,3R,5S)-2-[(1E)-3,3-difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-N-ethyl-, (5Z)-
Tafluprost ethyl amide

Biological Activity

[Description]:

Tafluprost ethyl amide is a prostaglandin derivative. Tafluprost ethyl amide is capable of intraocular pressure (IOP) reduction and influencing eyelash growth. Tafluprost ethyl amide can be used in antiglaucoma ophthalmic compositions or cosmetics[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Krupa M, et al. A Novel Convergent Synthesis of the Potent Antiglaucoma Agent Tafluprost. Molecules. 2017 Jan 31;22(2):217.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
609.3±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H33F2NO4

[ Molecular Weight ]:
437.520

[ Flash Point ]:
322.3±31.5 °C

[ Exact Mass ]:
437.237762

[ PSA ]:
78.79000

[ LogP ]:
2.66

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.559

Related Compounds