BU 226 HCl

Names

[ Name ]:
BU 226 HCl

[Synonym ]:
3-(4,5-Dihydro-1H-imidazol-2-yl)isoquinoline hydrochloride (1:1)
Isoquinoline, 3-(4,5-dihydro-1H-imidazol-2-yl)-, hydrochloride (1:1)

Biological Activity

[Description]:

BU226 hydrochloride is a selective imidazoline 2 (I2) receptors ligand with an Ki of 1.4 nM for I2 and an IC50 of 534.5 nM for I1. BU226 hydrochloride can be used for researching antidepressant[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Imidazoline Receptor

Signaling Pathways >> GPCR/G Protein >> Imidazoline Receptor

Research Areas >> Neurological Disease

[Target]

Ki: 1.4 nM (I2)[1] IC50: 534.5 nM (I1)[1]

[References]

[1]. Hudson AL, et al. Novel selective compounds for the investigation of imidazoline receptors. Ann N Y Acad Sci. 1999 Jun 21;881:81-91.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₁₂ClN₃

[ Molecular Weight ]:
233.697

[ Exact Mass ]:
233.071976

[ Storage condition ]:
-20°C

BU 226 HCl

Names

Biological Activity

Chemical & Physical Properties

Related Compounds