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AIC-292

Names

[ CAS No. ]:
1187917-12-9

[ Name ]:
AIC-292

Biological Activity

[Description]:

AIC-292 is a potent and selective inhibitor of HIV-1 nonnucleoside reverse transcriptase. AIC-292 inhibits wild-type HIV-1 laboratory strains at low nanomolar concentrations. AIC-292 displays potent antiviral in vivo efficacy in a mouse xenograft model. AIC-292 has the potential for the research of HIV-1 infection[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV
Research Areas >> Infection

[References]

[1]. Wildum S, et al. In vitro and in vivo activities of AIC292, a novel HIV-1 nonnucleoside reverse transcriptase inhibitor. Antimicrob Agents Chemother. 2013;57(11):5320-5329.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H12Cl2F2N4O2

[ Molecular Weight ]:
437.23

Related Compounds