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Lamotrigine-13C3

Names

[ CAS No. ]:
1188265-38-4

[ Name ]:
Lamotrigine-13C3

[Synonym ]:
BW 430C-13C3
Lamotrigine-13C3
Lamotrigin-13C3
LTG-13C3
Lamictal-13C3
Lamictal XR-13C3

Biological Activity

[Description]:

Lamotrigine-13C3 is the 13C-labeled Lamotrigine. Lamotrigine (BW430C) is a potent and orally active anticonvulsant or antiepileptic agent. Lamotrigine selectively blocks voltage-gated Na+ channels, stabilizing presynaptic neuronal membranes and inhibiting glutamate release. Lamotrigine can be used for the research of epilepsy, focal seizure, et al[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel
Signaling Pathways >> Autophagy >> Autophagy
Research Areas >> Neurological Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[3]

Chemical & Physical Properties

[ Molecular Formula ]:
C9H7Cl2N5

[ Molecular Weight ]:
259.06900

[ Exact Mass ]:
258.01800

[ PSA ]:
91.44000

[ LogP ]:
2.52110

Related Compounds