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Amino-PEG5-C2-acid

Names

[ CAS No. ]:
1191078-74-6

[ Name ]:
Amino-PEG5-C2-acid

[Synonym ]:
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-amino-
MFCD25424126
1-Amino-3,6,9,12,15-pentaoxaoctadecan-18-oic acid

Biological Activity

[Description]:

Amino-PEG5-C2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Gregory L. Verdine, et al. Stabilized polypeptide insulin receptor modulators. WO2014201370A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
446.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H27NO7

[ Molecular Weight ]:
309.356

[ Flash Point ]:
223.5±28.7 °C

[ Exact Mass ]:
309.178741

[ LogP ]:
-2.28

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.469

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds