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Amino-PEG9-acid

Names

[ CAS No. ]:
1191079-83-0

[ Name ]:
Amino-PEG9-acid

[Synonym ]:
1-Amino-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid
3,6,9,12,15,18,21,24,27-Nonaoxatriacontan-30-oic acid, 1-amino-
MFCD26127809

Biological Activity

[Description]:

Amino-PEG9-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Iwaoka E, et al. Improvement of monolithic solid material by utilization of spacer for identification of the target using affinity resins. Bioorg Med Chem Lett. 2009 Mar 1;19(5):1469-72.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
578.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H43NO11

[ Molecular Weight ]:
485.566

[ Flash Point ]:
303.6±30.1 °C

[ Exact Mass ]:
485.283600

[ LogP ]:
-3.71

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.470

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds