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Cassiaside C

Names

[ CAS No. ]:
119170-52-4

[ Name ]:
Cassiaside C

[Synonym ]:
cassiaside C
toralactone-9-O-gentiobioside
10-Hydroxy-7-methoxy-3-methyl-9-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-benzo[g]isochromen-1-one
toralactone 9-O-yl β-D-glucopyranosyl-(1->6)-β-D-glucopyranoside
toralactone-9-O-β-D-gentiobioside

Biological Activity

[Description]:

Cassiaside C (Toralactone 9-O-β-D-gentiobioside) is a naphthopyrone isolated from the seed of Cassia tora and has inhibitory activity on advanced glycation end products (AGE) formation in vitro[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

IC50: AGE formation[1]


[References]

[1]. Yu-Lin Diao, et al. A new comprehensive procedure for the quality control of Semen Cassiae and its application in evaluating commercially available material in China. Chin J Nat Med. 2013 Jul;11(4):433-41.

[2]. Dong Ho Jung, et al. Extract of Cassiae Semen and its major compound inhibit S100b-induced TGF-beta1 and fibronectin expression in mouse glomerular mesangial cells. Eur J Pharmacol. 2010 Sep 1;641(1):7-14.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H32O15

[ Molecular Weight ]:
596.53400

[ Exact Mass ]:
596.17400

[ PSA ]:
238.20000

[ Storage condition ]:
2-8℃

Related Compounds