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Omadacycline (mesylate)

Names

[ CAS No. ]:
1196800-40-4

[ Name ]:
Omadacycline (mesylate)

[Synonym ]:
(4S,4aS,5aR,12aS)-4,7-Bis(dimethylamino)-9-{[(2,2-dimethylpropyl)amino]methyl}-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide methanesulfonate (1:1)
2-Naphthacenecarboxamide, 4,7-bis(dimethylamino)-9-[[(2,2-dimethylpropyl)amino]methyl]-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)-, methanesulfonate (1:1) (salt)
Omadacycline (mesylate)

Biological Activity

[Description]:

Omadacycline mesylate is a new tetracycline antibiotic in the pipeline, which can inhibit the 30s subunit of bacterial ribosome.IC50 Value: N/ATarget: Antibacterialin vitro: in vivo: Clinical trial: Phase III Study to Compare the Safety and Efficacy of PTK-0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI).

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Infection

[References]

[1]. Schmitz J, Holzgrabe U. Amadacyclin - a new tetracycline antibiotic in the pipeline. Pharm Unserer Zeit. 2010 Mar;39(2):94-5.


[Related Small Molecules]

Puromycin 2HCl | Geneticin | Tunicamycin | Hygromycin B | Salinomycin | Avibactam sodium | Neomycin sulfate | Vaborbactam | Methicillin SodiuM | Rifampicin | Metronidazole | Carbenicillin disodium | Ceftazidime | Eravacycline dihydrochloride | cefotaxime sodium

Chemical & Physical Properties

[ Molecular Formula ]:
C30H44N4O10S

[ Molecular Weight ]:
652.756

[ Exact Mass ]:
652.277832

[ Storage condition ]:
2-8℃

Related Compounds