AVL-292
Names
[ CAS No. ]:
1202757-89-8
[ Name ]:
AVL-292
[Synonym ]:
N-{3-[(5-Fluoro-2-{[4-(2-methoxyethoxy)phenyl]amino}-4-pyrimidinyl)amino]phenyl}acrylamide
UNII-DRU6NG543J
S7173,CC-292
AVL 292
N-(3-(5-fluoro-2-(4-(2-methoxyethoxy)phenylamino)pyrimidin-4-ylamino)phenyl)acrylamide
Spebrutinib
2-Propenamide, N-[3-[[5-fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-
AVL-292
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: <0.5 nM (Btk)[1]
[In Vitro]
[Cell Assay]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Molecular Formula ]:
C22H22FN5O3
[ Molecular Weight ]:
423.440
[ Exact Mass ]:
423.170654
[ PSA ]:
104.12000
[ LogP ]:
2.95
[ Index of Refraction ]:
1.655
Safety Information
[ Hazard Codes ]:
Xi