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Citroside A

Names

[ CAS No. ]:
120330-44-1

[ Name ]:
Citroside A

[Synonym ]:
(3S,5R,8R)-3,5-dihydroxy-6,7-megastigmadien-9-one 5-O-β-D-glucopyranoside
citroside A <(5-dehydroxygrasshopper ketone-5-yl) 5-β-D-glucopyranoside>
4-[(4S,6R)-4-Hydroxy-2,2,6-trimethyl-6-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-cyclohexylidene]-but-3-en-2-one
citroside A [(5-dehydroxygrasshopper ketone-5-yl) 5-β-D-glucopyranoside]

Biological Activity

[Description]:

Citroside A is a megastigmane sesquiterpenoid with cytotoxic and anti-inflammatory activities. Citroside A displays potential effects against NO production with an IC50 of 34.25 μM. Citroside A exhibits pronounced cytotoxicity against SGC-7901 and HeLa cells with IC50 values of 27.52 μM and 29.51 μM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> NO Synthase
Research Areas >> Inflammation/Immunology

[References]

[1]. Rui Guo, et al. A new sesquiterpenoid with cytotoxic and anti-inflammatory activity from the leaves of Datura metel L. Nat Prod Res. 2021 Feb;35(4):607-613.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H30O8

[ Molecular Weight ]:
386.43700

[ Exact Mass ]:
386.19400

[ PSA ]:
136.68000

Related Compounds