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Sarafotoxin B trifluoroacetate salt

Names

[ CAS No. ]:
120972-53-4

[ Name ]:
Sarafotoxin B trifluoroacetate salt

[Synonym ]:
CSCKDMTDKECLYFCHQDVIW
Sarafotoxin 6b
M.W. 2564.00 C110H159N27O34S5
SRTX-B
SARAFOTOXIN B

Biological Activity

[Description]:

Sarafotoxin S6b is a vasoconstrictor peptide, and a non-selective endothelin receptor agonist. Sarafotoxin S6b can induce contraction in isolated human coronary arteries , the Ki values of Coronary artery, Saphenous vein and Coronary artery are 0.27, 0.55 and 19.5 nM, respectively[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor

[References]

[1]. P S Devadason et al. Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br J Pharmacol. 1997 May;121(2):253-63.

Chemical & Physical Properties

[ Density]:
1.298 g/cm3

[ Boiling Point ]:
2570.1ºC at 760 mmHg

[ Molecular Formula ]:
C110H159N27O34S5

[ Molecular Weight ]:
2563.92000

[ Flash Point ]:
1508.1ºC

[ Exact Mass ]:
2562.01000

[ PSA ]:
1121.31000

[ LogP ]:
3.20170

Related Compounds