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Ethyl vanillin

Names

[ CAS No. ]:
121-32-4

[ Name ]:
Ethyl vanillin

[Synonym ]:
burbonal
FEMA 2464
vanirome
EINECS 204-464-7
Bourbonal
3-Ethoxy-4-hydroxybenzaldehyde,Ethylvanillin
Vanilal
VANILLAL
ETHOVAN
3-ethoxy
VHR DQ CO2
ethylvanillin
4-hydroxy-3-ethoxybenzaldehyde
4-OH-3-OEtC6H3CHO
Vanirom
3-Ethoxy-4-hydroxybenzaldehyde
Vanbeenol
MFCD00006944
Ethyl Vanillin
Benzaldehyde, 3-ethoxy-4-hydroxy-
Ethavan

Biological Activity

[Description]:

Ethylvanillin is a flavorant, about three times as potent as vanillin and is used in the production of chocolate.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Others

[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
295.1±20.0 °C at 760 mmHg

[ Melting Point ]:
76 °C

[ Molecular Formula ]:
C9H10O3

[ Molecular Weight ]:
166.174

[ Flash Point ]:
119.0±15.3 °C

[ Exact Mass ]:
166.062988

[ PSA ]:
46.53000

[ LogP ]:
1.72

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.574

[ Water Solubility ]:
slightly soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CU6125000
CHEMICAL NAME :
Benzaldehyde, 3-ethoxy-4-hydroxy-
CAS REGISTRY NUMBER :
121-32-4
BEILSTEIN REFERENCE NO. :
1073761
LAST UPDATED :
199710
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C9-H10-O3
MOLECULAR WEIGHT :
166.19
WISWESSER LINE NOTATION :
VHR DQ CO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Human
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1590 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
760 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>7940 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4480 mg/kg/70D-I
TOXIC EFFECTS :
Cardiac - other changes Blood - changes in spleen Nutritional and Gross Metabolic - weight loss or decreased weight gain

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Fibroblast
DOSE/DURATION :
250 mg/L
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4743 No. of Facilities: 26 (estimated) No. of Industries: 2 No. of Occupations: 17 No. of Employees: 2343 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4743 No. of Facilities: 2917 (estimated) No. of Industries: 20 No. of Occupations: 42 No. of Employees: 53949 (estimated) No. of Female Employees: 31080 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
CU6125000

[ Packaging Group ]:
I; II; III

[ HS Code ]:
2912420000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2912420000

[ Summary ]:
2912420000 3-ethoxy-4-hydroxybenzaldehyde。Supervision conditions:None。VAT:17.0%。Tax rebate rate:13.0%。Lowest tariff:5.5%。General tariff:30.0%

Articles

[Studies on the chemical constituents of marine sponge Iotrochota sp].

Zhong Yao Cai 33(4) , 545-6, (2010)

To study the chemical constituents from the marine sponge Iotrochota sp.The compounds were isolated and purified by various column chromatography methods, and their structure wer identified cholestero...

Thermal tolerance and survival of Cronobacter sakazakii in powdered infant formula supplemented with vanillin, ethyl vanillin, and vanillic acid.

J. Food Sci. 77(9) , M523-7, (2012)

The thermal tolerance Cronobacter sakazakii was examined in sterile powdered infant formula (PIF) rehydrated at 58 °C in water or apple juice supplemented with vanillin, ethyl vanillin, or vanillic ac...

Dihydroagarofuranoid sesquiterpenes, a lignan derivative, a benzenoid, and antitubercular constituents from the stem of Microtropis japonica.

J. Nat. Prod. 71 , 1016-21, (2008)

Four new compounds, including two new dihydroagarofuranoid sesquiterpenes, 8-benzoyloxymutangin (1) and 15-acetoxyorbiculin G (2), a new lignan derivative, 9,9'- O-di-(Z)-feruloyl-(-)-secoisolaricires...


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Related Compounds