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Secretin (rat)

Names

[ CAS No. ]:
121028-49-7

[ Name ]:
Secretin (rat)

[Synonym ]:
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-GLN-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 RAT
H-His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Gln-Asp-Ser-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2
HSDGTFTSELSRLQDSARLQRLLQGLV-NH2
HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-GLN-ASP-SER-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
Secretin (33-59), rat

Biological Activity

[Description]:

Secretin (33-59), rat is a 27-aa peptide, acts on secretin receptor, enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease
Peptides

[Target]

Secretin receptor[2]


[In Vitro]

Secretin (33-59), rat inhibits adrenocorticotropic hormone (ACTH) release, and selectively suppresses the glucocorticoid response to ACTH of dispersed zona fasciculata-reticularis (ZF/R) cells[1]. Secretin retrograde messenger to facilitate GABA transmission in the rat cerebellum[2].

[References]

[1]. Nussdorfer GG, et al. Secretin, glucagon, gastric inhibitory polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus- pituitary-adrenal axis. Peptides. 2000 Feb;21(2):309-24.

[2]. Ng SS, et al. Secretin as a neuropeptide. Mol Neurobiol. 2002 Aug;26(1):97-107.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.505 g/cm3

[ Molecular Formula ]:
C129H216N42O42

[ Molecular Weight ]:
3027.35000

[ Exact Mass ]:
3025.61000

[ PSA ]:
1402.64000

Related Compounds