Etebenecid

Names

[ Name ]:
Etebenecid

[Synonym ]:
Ethebenecid
4-Diethylsulfamoyl-benzoic acid
Ethebenecide
4-[(Diethylamino)sulfonyl]benzoic acid
p-(Diethylsulfamoyl)benzoic acid
Urelim
Etebenecid
4-Diaethylsulfamoyl-benzoesaeure
4-Carboxy-N,N-diethylbenzenesulfonamide

Biological Activity

[Description]:

Etebenecid is a uricosuric agents, lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys, also inhibits penicillin tubular secretion.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.283g/cm3

[ Boiling Point ]:
416.5ºC at 760mmHg

[ Molecular Formula ]:
C₁₁H₁₅NO₄S

[ Molecular Weight ]:
257.30600

[ Flash Point ]:
205.7ºC

[ Exact Mass ]:
257.07200

[ PSA ]:
83.06000

[ LogP ]:
2.49610

[ Vapour Pressure ]:
1.11E-07mmHg at 25°C

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG8558300

CHEMICAL NAME :: Benzoic acid, p-(diethylsulfamoyl)-

CAS REGISTRY NUMBER :: 1213-06-5

BEILSTEIN REFERENCE NO. :: 2812421

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H15-N-O4-S

MOLECULAR WEIGHT :: 257.33

WISWESSER LINE NOTATION :: QVR DSWN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 96 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 38,102,1983

Safety Information

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%