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N-ε-propargyloxycarbonyl-L-lysine

Names

[ CAS No. ]:
1215204-46-8

[ Name ]:
N-ε-propargyloxycarbonyl-L-lysine

Biological Activity

[Description]:

N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Labeling of N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH)-carrying cellular proteins, such as Sec61β, Htt74Q and the histone H3 variant H3.3, with a sensitive Raman tag by click chemistry for molecular hyperspectral SRS imaging[1].

[References]

[1]. Kyung Jin Lee, et al. Site-Specific Labeling of Proteins Using Unnatural Amino Acids. Mol Cells. 2019 May 31;42(5):386-396.

[2]. Enke HEIKE, et al. Modified microcystins and nodularins.WO2018206715A2

Chemical & Physical Properties

[ Molecular Formula ]:
C10H16N2O4

[ Molecular Weight ]:
228.24504

Related Compounds