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AR-AO 14418-d3

Names

[ CAS No. ]:
1216908-63-2

[ Name ]:
AR-AO 14418-d3

Biological Activity

[Description]:

AR-A014418-d3 (AR 0133418-d3) is the deuterium labeled AR-A014418. AR-A014418 is a potent, selective, and ATP-competitive GSK3β inhibitor (IC50=104 nM; Ki=38 nM)[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> GSK-3
Research Areas >> Cancer
Research Areas >> Metabolic Disease
Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3

[References]

[1]. Bhat R, Xue Y, Berg S, Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418. J Biol Chem. 2003 Nov 14;278(46):45937-45.

Chemical & Physical Properties

[ Molecular Formula ]:
C12H12N4O4S

[ Molecular Weight ]:
308.31308

[ Storage condition ]:
2-8°C

Related Compounds