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FTI 276 TFA

Names

[ CAS No. ]:
1217471-51-6

[ Name ]:
FTI 276 TFA

Biological Activity

[Description]:

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Farnesyl Transferase

[Target]

IC50: 0.9 nM (PFT, Plasmodium falciparum), 0.5 nM (PFT, human)[1].

[References]

[1]. Chakrabarti D, et al. Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.J Biol Chem. 2002 Nov 1; 277(44):42066-73. Epub 2002 Aug 22.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₈F₃N₃O₅S₂

[ Molecular Weight ]:
547.61

[ Storage condition ]:
2-8℃

Related Compounds