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(-)-Dizocilpine

Names

[ CAS No. ]:
121917-57-5

[ Name ]:
(-)-Dizocilpine

[Synonym ]:
5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5S,10R)-, (2Z)-2-butenedioate (1:1)
5H-Dibenzo[a,d]cyclohepten-5,10-imine,10,11-dihydro-5-methyl-,(5R,10S)
(1R,9S)-1-Methyl-16-azatetracyclo[7.6.1.0.0]hexadeca-2,4,6,10,12,14-hexaene (2Z)-but-2-enedioate (1:1)
5H-Dibenzo[a,d]cyclohepten-5,10-imine, 10,11-dihydro-5-methyl-, (5R,10S)-, (2Z)-2-butenedioate (1:1)
(+)-MK 801 maleate
(+)-10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-diyldiammonium maleate
(1S,9R)-1-Methyl-16-azatetracyclo[7.6.1.0.0]hexadeca-2,4,6,10,12,14-hexaene (2Z)-2-butenedioate (1:1)
(1S,9R)-1-Methyl-16-azatetracyclo[7.6.1.0.0]hexadeca-2,4,6,10,12,14-hexaene (2Z)-but-2-enedioate (1:1)
(1R,9S)-1-Methyl-16-azatetracyclo[7.6.1.0.0]hexadeca-2,4,6,10,12,14-hexaene (2Z)-2-butenedioate (1:1)
DIZOCILPINE MALEATE
(-)-MK-801 MALEATE
(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (Z)-2-Butenedioate (1:1)
(-)-MK 801 maleate
Neurogard
(5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene (2Z)-but-2-enedioate (1:1)
DIZOCILPINE MALEATE, (-)-

Biological Activity

[Description]:

(-)-MK 801 Maleate is the enantiomer of (+)-MK-801. (+)-MK 801 Maleate is a potent, selective and non-competitive NMDA receptor antagonist.

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease

[Related Small Molecules]

(+)-MK 801 Maleate | CNQX | N-Methyl-D-aspartic acid | ifenprodil tartrate | D-AP5(mM/ml) | DNQX | Ro 25-6981 maleate | Flupirtine maleate | Mibampator | CX546 | Naspm | Talampanel | Centrophenoxine hydrochloride | 24-Hydroxycholesterol

Chemical & Physical Properties

[ Boiling Point ]:
320.3ºC at 760 mmHg

[ Molecular Formula ]:
C20H19NO4

[ Molecular Weight ]:
337.369

[ Flash Point ]:
152.6ºC

[ Exact Mass ]:
337.131409

[ PSA ]:
86.63000

[ LogP ]:
3.19110

[ Vapour Pressure ]:
0.000321mmHg at 25°C

[ Storage condition ]:
-20℃

[ Water Solubility ]:
DMSO: >20 mg/mL

Safety Information

[ Safety Phrases ]:
22-24/25

[ WGK Germany ]:
3

[ RTECS ]:
HP1093575


Related Compounds