Propylparaben-d4
Names
[ CAS No. ]:
1219802-67-1
[ Name ]:
Propylparaben-d4
[Synonym ]:
<i>n</i>-propyl 4-hydroxybenzoate-2,3,5,6-d<sub>4</sub>
Biological Activity
[Description]:
Propylparaben-d4 is the deuterium labeled Propylparaben[1]. Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial preservative which can be produced naturally by plants and bacteria. Propylparaben is prevalently used in cosmetics, pharmaceuticals, and foods. Propylparaben disrupts antral follicle growth and steroidogenic function by altering the cell-cycle, apoptosis, and steroidogenesis pathways. Propylparaben also decreases sperm number and motile activity in rats[2][3][4].
[Related Catalog]:
[In Vitro]
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C10H8D4O3
[ Molecular Weight ]:
184.22500
[ Exact Mass ]:
184.10400
[ PSA ]:
46.53000
[ LogP ]:
1.95900