G 0507

Names

[ Name ]:
G 0507

Biological Activity

[Description]:

G0507, a pyrrolopyrimidinedione compound, is a potent LolCDE ABC Transporter inhibitor. G0507 is a inhibitor of Escherichia coli growth and induces the extracytoplasmic σE stress response. G0507 acts as a chemical probe to dissect lipoprotein trafficking in Gram-negative bacteria[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Nickerson NN, et al. A Novel Inhibitor of the LolCDE ABC Transporter Essential for Lipoprotein Trafficking in Gram-Negative Bacteria. Antimicrob Agents Chemother. 2018 Mar 27;62(4).

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₅N₃O₃S

[ Molecular Weight ]:
353.40

Safety Information

[ Hazard Codes ]:
Xi

G 0507

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds