GBLD345

Names

[ CAS No. ]:
122479-08-7

[ Name ]:
GBLD345

[Synonym ]:
2-(4-Aminophenyl)-3-methoxy-N-(3-methoxybenzyl)imidazo[1,2-b]pyridazin-6-amine
Imidazo[1,2-b]pyridazin-6-amine, 2-(4-aminophenyl)-3-methoxy-N-[(3-methoxyphenyl)methyl]-
GBLD-345

Biological Activity

[Description]:

GBLD345, a nonbenzodiazepine anxiolytic agent, is a non- selective, potent GABAA receptor positive allosteric modulator (PAM)[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor
Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[References]

[1]. Mohd Imran, Mohammad Asif Study of Various Pyridazine and Phthalazine Drugs with Diverse Therapeutical and Agrochemical Activities. Russ J Bioorg Chem 46, 745-767 (2020).

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C21H21N5O2

[ Molecular Weight ]:
375.424

[ Exact Mass ]:
375.169525

[ LogP ]:
2.33

[ Index of Refraction ]:
1.658

Related Compounds