<Suppliers Price>

E3 ligase Ligand 8

Names

[ CAS No. ]:
1225383-33-4

[ Name ]:
E3 ligase Ligand 8

Biological Activity

[Description]:

E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 8 can be connected to the ligand for protein by a linker to form PROTACs or SNIPERs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[References]

[1]. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

Chemical & Physical Properties

[ Molecular Formula ]:
C31H34N2O6

[ Molecular Weight ]:
530.61

Related Compounds