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Bi-linderone

Names

[ CAS No. ]:
1227375-09-8

[ Name ]:
Bi-linderone

[Synonym ]:
Spiro[4.5]deca-2,7-diene-1,4-dione, 9-[(3,4-dimethoxy-2,5-dioxo-3-cyclopenten-1-ylidene)methoxymethyl]-2,3,8-trimethoxy-6,10-diphenyl-, (6R,9R,10S)-
(6R,9R,10S)-9-[(3,4-Dimethoxy-2,5-dioxo-3-cyclopenten-1-ylidene)(methoxy)methyl]-2,3,8-trimethoxy-6,10-diphenylspiro[4.5]deca-2,7-diene-1,4-dione

Biological Activity

[Description]:

Bi-linderone is isolated as racemate from the traditional Chinese medicinal plant Lindera aggregata. Bi-linderone has activity against glucosamine-induced insulin resistance in HepG2 cells at a concentration of 1 μg/mL[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Wang F, et al. Bi-linderone, a highly modified methyl-linderone dimer from Lindera aggregata with activity toward improvement of insulin sensitivity in vitro. Org Lett. 2010 May 21;12(10):2354-7.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
835.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C34H32O10

[ Molecular Weight ]:
600.61

[ Flash Point ]:
344.5±34.3 °C

[ Exact Mass ]:
600.199524

[ PSA ]:
123.66000

[ LogP ]:
3.20

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.613

Related Compounds