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Anti-Human IL-17A

Names

[ CAS No. ]:
1229022-83-6

[ Name ]:
Anti-Human IL-17A

Biological Activity

[Description]:

Anti-Human IL-17A is a fully human anti-interleukin-17A monoclonal antibody. Anti-Human IL-17A can be used for research in psoriasis pathogenesis[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[Target]

IL-17A[1]


[In Vitro]

IL-17A 是一种介导炎症反应的细胞因子,由 T 淋巴细胞和其他免疫细胞产生。它在多种炎症性疾病中起着重要作用,例如类风湿性关节炎、银屑病、炎症性肠病等。IL-17A 通过刺激靶细胞产生促炎症细胞因子,如 IL-6、IL-8、G-CSF 等,从而引发炎症反应。

[References]

[1]. Reich K, et al. Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, exhibits minimal immunogenicity in patients with moderate-to-severe plaque psoriasis. Br J Dermatol. 2017 Mar;176(3):752-758.  

Chemical & Physical Properties

[ Storage condition ]:
2-8°C


Related Compounds