2,6-Dimethyl-L-tyrosine

Names

[ Name ]:
2,6-Dimethyl-L-tyrosine

[Synonym ]:
aminoacid 2,6-dimethyl-L-tyrosine
2,5-DIMETHOXYPHENYL ISOTHIOCYANATE
2,6-Dimethyl-L-tyrosine
L-Tyrosine, 2,6-dimethyl-
2',6'-Dimethyltyrosine
L-Tyrosine,2,6-dimethyl

Biological Activity

[Description]:

2,6-Dimethyl-L-tyrosine (Dmt) is a tyrosine derivative that enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

Research Areas >> Neurological Disease

[References]

[1]. Fujita Y, et al. Studies on the structure-activity relationship of 2',6'-dimethyl-l-tyrosine (Dmt) derivatives: bioactivity profile of H-Dmt-NH-CH(3). Bioorg Med Chem Lett. 2005 Feb 1;15(3):599-602.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
412.8±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₅NO₃

[ Molecular Weight ]:
209.242

[ Flash Point ]:
203.4±28.7 °C

[ Exact Mass ]:
209.105194

[ PSA ]:
83.55000

[ LogP ]:
1.30

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.592

Safety Information

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%