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Antibacterial agent 18

Names

[ CAS No. ]:
1239602-35-7

[ Name ]:
Antibacterial agent 18

[Synonym ]:
TCPA
H3TCBPA
tris(4-carboxylphenylduryl)amine
tris(4'-carboxybiphenyl)amine
4',4''',4'''''-nitrilotris(([1,1'-biphenyl]-4-carboxylic acid))

Biological Activity

[Description]:

Antibacterial agent 18 is a multi-arm AIE molecule extracted from patent CN110123801A, compound 23. Antibacterial agent 18 can be used for resisting Gram-positive and Gram-negative bacteria. Antibacterial agent 18 can be conjugated in the cell wall of rigid arm configuration insertion bacterium, and block cell wall turns sugar and turns peptide process, to inhibit or kill bacterium[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Antibacterial agent 18 (0.004-4 μg/mL; 24 h) inhibits the growth of Gram-positive and Gram-negative bacteria, with MICs ranging from 0.008-1 μg/mL[1].

[References]

[1]. Jiang XY, et, al. The purposes and antibacterials of a kind of multi-arm AIE molecule in preparation antibacterials. CN110123801A.

Chemical & Physical Properties

[ Density]:
1.333±0.06 g/ml(Predicted)

[ Boiling Point ]:
874.1±65.0℃(Predicted)

[ Molecular Formula ]:
C39H27NO6

[ Molecular Weight ]:
605.63500

[ Exact Mass ]:
605.18400

[ PSA ]:
115.14000

[ LogP ]:
9.25200

[ Storage condition ]:
2-8℃

Related Compounds