FR-901235

Names

[ CAS No. ]:
124190-19-8

[ Name ]:
FR-901235

[Synonym ]:
2-Acetonyl-2,4,9-trihydroxy-6-methoxy-7-methyl-1H-phenalene-1,3(2H)-dione
1H-Phenalene-1,3(2H)-dione,2,4,9-trihydroxy-6-methoxy-7-methyl-2-(2-oxopropyl)-,(-)

Biological Activity

[Description]:

FR-901235 is a new type of immunoactive substance produced by an imperfect fungus, Paecilomyces carneus F-4882. FR-901235 partially restored the impaired delayed-type hypersensitivity to sheep red blood cells in tumor-bearing mice[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. T Shibata, et al. A new immunomodulator, FR-901235. J Antibiot (Tokyo). 1989 Sep;42(9):1356-61.  

Chemical & Physical Properties

[ Density]:
1.501g/cm3

[ Boiling Point ]:
681.8ºC at 760mmHg

[ Molecular Formula ]:
C18H16O7

[ Molecular Weight ]:
344.31500

[ Flash Point ]:
252.6ºC

[ Exact Mass ]:
344.09000

[ PSA ]:
121.13000

[ LogP ]:
1.65720

[ Vapour Pressure ]:
1.6E-19mmHg at 25°C

[ Index of Refraction ]:
1.686

Related Compounds