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EltroMbopag Methyl Ester

Names

[ CAS No. ]:
1246929-01-0

[ Name ]:
EltroMbopag Methyl Ester

[Synonym ]:
Methyl 3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylate
Eltrombopag Methyl Ester
[1,1'-Biphenyl]-3-carboxylic acid, 3'-[(2Z)-2-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-, methyl ester

Biological Activity

[Description]:

Eltrombopag methyl ester is a derivative of Eltrombopag, which is a thrombopoietin (Tpo) receptor agonist, which can promote platelet production and is used in research related to specific types of thrombocytopenia[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> Immunology/Inflammation >> Thrombopoietin Receptor

[References]

[1]. Polymorphs of eltrombopag and eltrombopag salts and processes for preparation thereof. WO2010114943.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
626.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H24N4O4

[ Molecular Weight ]:
456.49

[ Flash Point ]:
332.7±34.3 °C

[ Exact Mass ]:
456.179749

[ PSA ]:
103.59000

[ LogP ]:
3.82

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.641

Related Compounds