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Vomicine

Names

[ CAS No. ]:
125-15-5

[ Name ]:
Vomicine

[Synonym ]:
Vomicin
12-Hydroxy-N-methylpseudostrychnine
(4aR,6aS,12aS,12bR,12cS)-10-hydroxy-15-methyl-4a,5,12,12a,12b,12c-hexahydro-11H-6a,4-(ethanoiminomethano)-1-oxa-10b-azacyclohepta[1,2,3-cd]fluoranthene-6,11(2H)-dione
(1S,10S,22R,23R,24S)-15-Hydroxy-4-methyl-9-oxa-4,13-diazahexacyclo[11.6.5.0.0.0.0]tetracosa-6,14,16,18-tetraene-12,20-dione
16,19-Secostrychnidine-10,16-dione, 4-hydroxy-19-methyl-
Strychnicine
4-Hydroxy-19-methyl-16,19-secostrychnidine-10,16-dione
16,19-Secostrychnidine-10,16-dione,4-hydroxy-19-methyl
12H-6a,4-(Ethanoiminomethano)indolo[3,2,1-ij]oxepino[2,3,4-de]quinoline-6,12(2H)-dione, 4a,5,13,13a,13b,13c-hexahydro-10-hydroxy-16-methyl-, (4aR,6aS,13aS,13bR,13cS)-
4-hydroxy-19-methyl-16,19-seco-strychnidine-10,16-dione
4-hydroxy-icajine
Vomicine
4-hydroxy-19-methyl-16,19-seco-strychnidin-10,16-dione

Biological Activity

[Description]:

Vomicine, an alkaloid isolated from seeds of S. nux-vomica, shows antidiabetic activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Bhati R, et al. Strychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity. J Ayurveda Integr Med. 2012 Apr;3(2):80-4.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
636.9±55.0 °C at 760 mmHg

[ Melting Point ]:
286-290℃ (dec.)

[ Molecular Formula ]:
C22H24N2O4

[ Molecular Weight ]:
380.437

[ Flash Point ]:
339.0±31.5 °C

[ Exact Mass ]:
380.173615

[ PSA ]:
70.08000

[ LogP ]:
0.47

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.699

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds