8-Prenylluteone

Names

[ Name ]:
8-Prenylluteone

[Synonym ]:
3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-4H-chromen-4-one
4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-

Biological Activity

[Description]:

8-Prenylluteone is a HIV-1 protease inhibitor, with an IC50 of 4 μM[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease

[References]

[1]. Lee J, et, al. Prenylisoflavonoids from Erythrina senegalensis as novel HIV-1 protease inhibitors. Planta Med. 2009 Feb;75(3):268-70.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
668.9±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₂₆O₆

[ Molecular Weight ]:
422.47

[ Flash Point ]:
229.3±25.0 °C

[ Exact Mass ]:
422.172943

[ PSA ]:
111.13000

[ LogP ]:
7.18

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.650

8-Prenylluteone

Names

Biological Activity

Chemical & Physical Properties

Related Compounds