Obtusalin

Names

[ Name ]:
Obtusalin

[Synonym ]:
Obtusalin

Biological Activity

[Description]:

Obtusalin is a triterpenoid found in R. dauricum for the first time and shows UV absorption at 210 nm. Obtusalin has some antibacterial activity[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Obtusalin (0.781-100 µg/mL, 24 h) has antibacterial activity against Enterococcus faecalis ATCC 10541, Providensia smartii ATCC 29916, Staphylococcus aureus ATCC 25922 and Escherichia coli ATCC 8739 with the MIC values of 50, 100, 50 and 100 μg/mL, respectively[1].

[References]

[1]. Jiang-Ling Li, et al. Antibacterial constituents from Melodinus suaveolens. Chin J Nat Med. 2015 Apr;13(4):307-10. doi: 10.1016/S1875-5364(15)30020-0.

[2]. Helen L Alvarado, et al. Development and validation of a high-performance liquid chromatography method for the quantification of ursolic/oleanic acids mixture isolated from Plumeria obtusa. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Mar 1;983-984:111-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₅₀O₂

[ Molecular Weight ]:
442.73