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GB-110

Names

[ CAS No. ]:
1252806-70-4

[ Name ]:
GB-110

Biological Activity

[Description]:

GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR)
Research Areas >> Inflammation/Immunology

[Target]

Protease activated receptor 2[1]


[References]

[1]. Barry GD, et al. Novel agonists and antagonists for human protease activated receptor 2. J Med Chem. 2010 Oct 28;53(20):7428-40.

Chemical & Physical Properties

[ Molecular Formula ]:
C33H48N6O5

[ Molecular Weight ]:
608.77

[ Storage condition ]:
2-8°C

Related Compounds