BACE-IN-1

BACE-IN-1 (Compound 13) is a substituted lmidazo[1 ,2-a]pyridine derivative which can inhibit β-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment of diseases in which BACE is involved, such as Alzheimer's disease.

Signaling Pathways >> Neuronal Signaling >> Beta-secretase

Research Areas >> Neurological Disease

[1]. Adnan M.M. Mjalli, et al. SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE AS β-SECRETASE INHIBITORS. WO 2010126745 A1

MK-8931 | LY2886721 | AZD3293(Lanabecestat) | LY2811376 | Epiberberine chloride | AZD3839 | LX-2343 | PF-06751979 | Sophoflavescenol | BACE1-IN-1 | β-Secretase Inhibitor IV