Spautin-1
Names
[ CAS No. ]:
1262888-28-7
[ Name ]:
Spautin-1
[Synonym ]:
spautin-1, autophagy inhibitor (6-fluoro-n-(4-fluorobenzyl)quinozaline-4-amine)
6-fluoro-n-(4-fluorobenzyl)quinazolin-4-amine
4-Quinazolinamine, 6-fluoro-N-[(4-fluorophenyl)methyl]-
6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine
Spautin 1
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
[In Vivo]
[Cell Assay]
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
419.6±40.0 °C at 760 mmHg
[ Molecular Formula ]:
C15H11F2N3
[ Molecular Weight ]:
271.265
[ Flash Point ]:
207.6±27.3 °C
[ Exact Mass ]:
271.092102
[ PSA ]:
37.81000
[ LogP ]:
3.40
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.672
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H318
[ Precautionary Statements ]:
P280-P305 + P351 + P338
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
22-41
[ Safety Phrases ]:
26-39
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
PLoS ONE 10 , e0131484, (2015)
Diarrhea is a prevalent pathological condition frequently associated to the colonization of the small intestine by enterotoxigenic Escherichia coli (ETEC) strains, known to be endemic in developing co...
Photosynthetic production of enantioselective biocatalysts.Microb. Cell Fact. 14 , 53, (2015)
Global resource depletion poses a dramatic threat to our society and creates a strong demand for alternative resources that do not compete with the production of food. Meeting this challenge requires ...
Outer-membrane translocation of bulky small molecules by passive diffusion.Proc. Natl. Acad. Sci. U. S. A. 112 , E2991-9, (2015)
The outer membrane (OM) of gram-negative bacteria forms a protective layer around the cell that serves as a permeability barrier to prevent unrestricted access of noxious substances. The permeability ...