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Mal-PEG5-acid

Names

[ CAS No. ]:
1286755-26-7

[ Name ]:
Mal-PEG5-acid

[Synonym ]:
1-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
3,6,9,12,15-Pentaoxaoctadecan-18-oic acid, 1-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-
MAL-PEG5-COOH
Mal-PEG5-acid

Biological Activity

[Description]:

Mal-PEG5-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
549.3±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H27NO9

[ Molecular Weight ]:
389.398

[ Flash Point ]:
286.0±30.1 °C

[ Exact Mass ]:
389.168579

[ LogP ]:
-1.80

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.505

Related Compounds