PF-04753299
Names
[ CAS No. ]:
1289620-49-0
[ Name ]:
PF-04753299
Biological Activity
[Description]:
PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1].
[Related Catalog]:
[Target]
IC50: bacterial[1]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C18H21NO4S
[ Molecular Weight ]:
347.42900
[ Exact Mass ]:
347.11900
[ PSA ]:
95.34000
[ LogP ]:
4.51600
Safety Information
[ RIDADR ]:
NONH for all modes of transport