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N-Boc-PEG7-alcohol

Names

[ CAS No. ]:
1292268-13-3

[ Name ]:
N-Boc-PEG7-alcohol

[Synonym ]:
2-Methyl-2-propanyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicos-1-yl)carbamate
Carbamic acid, N-(20-hydroxy-3,6,9,12,15,18-hexaoxaeicos-1-yl)-, 1,1-dimethylethyl ester
MFCD29049415

Biological Activity

[Description]:

N-Boc-PEG7-alcohol is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Julie Moreau, et al. Modular Synthesis of Bifunctional Linkers for Materials Science. European Journal of OrganicChemistry , 2011 ( 9 ) , 1641-1644.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
521.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H39NO9

[ Molecular Weight ]:
425.514

[ Flash Point ]:
269.0±30.1 °C

[ Exact Mass ]:
425.262482

[ LogP ]:
-1.38

[ Vapour Pressure ]:
0.0±3.1 mmHg at 25°C

[ Index of Refraction ]:
1.463

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds