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Amino-PEG10-OH

Names

[ CAS No. ]:
129449-09-8

[ Name ]:
Amino-PEG10-OH

[Synonym ]:
29-Amino-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol
3,6,9,12,15,18,21,24,27-Nonaoxanonacosan-1-ol, 29-amino-
MFCD28385478

Biological Activity

[Description]:

Amino-PEG10-OH is non-cleavable 10 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. James Bailey, et al. Non peptidic heterobivalent molecules for treating inflammatory diseases. WO2018134731A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
533.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H43NO10

[ Molecular Weight ]:
457.556

[ Flash Point ]:
276.3±28.7 °C

[ Exact Mass ]:
457.288696

[ LogP ]:
-4.24

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.466

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds