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BI-9667

Names

[ CAS No. ]:
1295298-26-8

[ Name ]:
BI-9667

Biological Activity

[Description]:

CCR1 antagonist 8 (compound 19n), a third azaindazole series compound, is a CCR1 antagonist clinical candidate, with an IC50 of 1.8 nM in Ca2+ flux assay[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> CCR
Signaling Pathways >> Immunology/Inflammation >> CCR
Research Areas >> Inflammation/Immunology

[Target]

CCR1:1.8 nM (IC50, in Ca2+ flux assay)


[References]

[1]. Harcken C, et al. Identification of novel azaindazole CCR1 antagonist clinical candidates. Bioorg Med Chem Lett. 2019 Feb 1;29(3):441-448.

Chemical & Physical Properties

[ Molecular Formula ]:
C22H18FN5O3S

[ Molecular Weight ]:
451.47

Related Compounds