Dehydrocorydaline nitrate

Names

[ Name ]:
Dehydrocorydaline nitrate

[Synonym ]:
2,3,9,10-Tetramethoxy-13-methyl-5,6-dihydroisoquinolino[3,2-a]isoquinolinium nitrate

Biological Activity

[Description]:

Dehydrocorydaline nitrate is isolated from Corydalis edulis Maxim with anti-malarial effects. Dehydrocorydaline nitrate shows strong anti-malarial effects (IC50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Parasite

Research Areas >> Infection

[Target]

IC50: 38 nM (P. falciparum 3D7 strain)[1]

[References]

[1]. Nonaka M, et al. Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts. Malar J. 2018 Jun 25;17(1):244. doi: 10.1186/s12936-018-2392-4.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₄N₂O₇

[ Molecular Weight ]:
428.435

[ Exact Mass ]:
428.158356

[ PSA ]:
109.68000

[ LogP ]:
3.97730

[ Storage condition ]:
2-8℃

Dehydrocorydaline nitrate

Names

Biological Activity

Chemical & Physical Properties

Related Compounds