7-Hydroxyisoflavone

Names

[ Name ]:
7-Hydroxyisoflavone

[Synonym ]:
Isoflavone,7-hydroxy-(6CI,7CI,8CI)
4H-1-Benzopyran-4-one, 7-hydroxy-3-phenyl-
7-hydroxy-isoflavone
7-Hydroxyisoflavone
7-Hydroxy-3-phenyl-chromen-4-one
7-hydroxy-3-phenyl-4H-1-benzopyran-4-one
7-hydroxy-3-phenylchromen-4-one
MFCD00017701
7-Hydroxy-3-phenyl-4H-chromen-4-one
4H-1-Benzopyran-4-one,7-hydroxy-3-phenyl

Biological Activity

[Description]:

7-Hydroxyisoflavone (compound 3) is a natural isoflavone compound[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Taj Ur Rahman, et al. Spectroscopic and density functional theory studies of 7-hydroxy-3'-methoxyisoflavone: A new isoflavone from the seeds of Indigofera heterantha (Wall). Spectrochim Acta A Mol Biomol Spectrosc. 2015 Sep 5:148:375-81.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
450.1±45.0 °C at 760 mmHg

[ Melting Point ]:
214.0 to 218.0 °C

[ Molecular Formula ]:
C₁₅H₁₀O₃

[ Molecular Weight ]:
238.238

[ Flash Point ]:
176.3±22.2 °C

[ Exact Mass ]:
238.062988

[ PSA ]:
50.44000

[ LogP ]:
3.02

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.666

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ3100255

CHEMICAL NAME :: 4H-1-Benzopyran-4-one, 7-hydroxy-3-phenyl-

CAS REGISTRY NUMBER :: 13057-72-2

BEILSTEIN REFERENCE NO. :: 0193534

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C15-H10-O3

MOLECULAR WEIGHT :: 238.25

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #3415394

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #3415394

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2430 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 24(9),38,1990

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #3415394

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-37/39

[ RTECS ]:
DJ3100255

[ HS Code ]:
2914400090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914400090

[ Summary ]:
2914400090 other ketone-alcohols and ketone-aldehydes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%