2,2':5',2''-Terthien-5-ylmethanol

Names

[ Name ]:
2,2':5',2''-Terthien-5-ylmethanol

[Synonym ]:
2,2':5',2''-Terthien-5-ylmethanol
2,2':5',2''-Terthiophen-5-ylmethanol
[2,2':5',2''-Terthiophene]-5-methanol

Biological Activity

[Description]:

α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Jae-Seung Lee, et al. α-Terthienylmethanol, isolated from Eclipta prostrata, induces apoptosis by generating reactive oxygen species via NADPH oxidase in human endometrial cancer cells. J Ethnopharmacol. 2015, 169.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
424.7±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₀OS₃

[ Molecular Weight ]:
278.41

[ Flash Point ]:
210.6±27.3 °C

[ Exact Mass ]:
277.989380

[ PSA ]:
104.95000

[ LogP ]:
4.38

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.687

Safety Information

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%