SCO-L-Lysine

Names

[ Name ]:
SCO-L-Lysine

[Synonym ]:
l-lysine, n6-[(2-cyclooctyn-1-yloxy)carbonyl]-

Biological Activity

[Description]:

SCO-L-Lysine contains a SCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups. SCO-L-Lysine can be incorporated into the protein of interest by the tRNAPyl/PylRSAF synthetase[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Anandi Kugele, et al. In situ EPR spectroscopy of a bacterial membrane transporter using an expanded genetic code. Chem Commun (Camb). 2021 Dec 3;57(96):12980-12983.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₂₄N₂O₄

[ Molecular Weight ]:
296.36200

[ Exact Mass ]:
296.17400

[ PSA ]:
101.65000

[ LogP ]:
2.72210